Farrell Lab

Computational Neuropathology Lab at Icahn School of Medicine

Publications


Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes


Kurt Farrell, Jack Humphrey, Timothy Chang, Yi Zhao, Yuk Yee Leung, Pavel P Kuksa, Vishakha Patil, Wan-Ping Lee, Amanda B Kuzma, Otto Valladares, others

Nature communications, vol. 15, Nature Publishing Group UK London, 2024, p. 7880


Chronic traumatic encephalopathy (CTE): criteria for neuropathological diagnosis and relationship to repetitive head impacts


Ann C McKee, Thor D Stein, Bertrand R Huber, John F Crary, Kevin Bieniek, Dennis Dickson, Victor E Alvarez, Jonathan D Cherry, Kurt Farrell, Morgane Butler, others

Acta neuropathologica, vol. 145, Springer, 2023, pp. 371--394


Artificial intelligence-derived neurofibrillary tangle burden is associated with antemortem cognitive impairment


Gabriel A Marx, Daniel G Koenigsberg, Andrew T McKenzie, Justin Kauffman, Russell W Hanson, Kristen Whitney, Maxim Signaevsky, Marcel Prastawa, Megan A Iida, Charles L White III, others

Acta Neuropathologica Communications, vol. 10, Springer, 2022, p. 157


Genome-wide association study and functional validation implicates JADE1 in tauopathy


Kurt Farrell, SoongHo Kim, Natalia Han, Megan A Iida, Elias M Gonzalez, Marcos Otero-Garcia, Jamie M Walker, Timothy E Richardson, Alan E Renton, Shea J Andrews, others

Acta neuropathologica, vol. 143, Springer, 2022, pp. 33--53


Interpretable deep learning of myelin histopathology in age-related cognitive impairment


Andrew T McKenzie, Gabriel A Marx, Daniel Koenigsberg, Mary Sawyer, Megan A Iida, Jamie M Walker, Timothy E Richardson, Gabriele Campanella, Johannes Attems, Ann C McKee, others

Acta Neuropathologica Communications, vol. 10, Springer, 2022, p. 131


High-resolution temporal and regional mapping of MAPT expression and splicing in human brain development


Marco M Hefti, Kurt Farrell, SoongHo Kim, Kathryn R Bowles, Mary E Fowkes, Towfique Raj, John F Crary

PloS one, vol. 13, Public Library of Science San Francisco, CA USA, 2018, pp. e0195771


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